Anthelmintics for Treatment of Parasites Animals Essays

Anthelmintics for Treatment of Parasites Animals Essays Anthelmintics for Treatment of Parasites Animals Essay Anthelmintics for Treatment of Parasites Animals Essay Vermifuges opposition is a cardinal issue within the veterinary field, to a great extent impacting carnal public assistance and the agricultural industries. ( Wolstenholme, Fairweather et Al. 2004 ) . Vermifuges are used as preventives and for the intervention of assorted parasites in animate beings, ruminants being the largest group, which the drugs mark. Of the many categories of vermifuges used there are three major categories used in the intervention and control of GI roundworms in sheep ; benzimidazoles / pro-benzimidazoles, imidazothiazoles/ tetrahydropyrimidines and avermectins/milbemycins. Each of these drugs categories have different mechanisms of action but all consequence merely the parasite holding minimum consequence on the host. This issue is of import when the weights of animate beings is unknown and an over dosage may be given. ( Urquhart 1996 ) . The category benzimidazoles/ pro-benzimidazoles consist of fenbendazole, oxfendazole, albendazole and other similar moving drugs. They target a protein ( beta tubulin ) distributed within microtubules, and both plasma and mitochondrial membranes. These aid the formation of farther microtubules, which in bend consequences in a decrease in glucose consumption and protein secernment, taking to decease by famishment. ( Taylor, Coop et Al. 2007 ) . This group chiefly effects nematodes including their eggs and has a low, sometimes negligible toxicity to the host. ( Urquhart 1996 ; Taylor, Coop et Al. 2007 ) . Resistance against vermifuges occurs the most extensively within this category. Imidazothiazoles/ tetrahydropyrimidines include four chief drugs levamisole, pyrantel, morantel and tetramisole. ( Urquhart 1996 ) . Levamisole is one of the chief drugs used against roundworms in sheep, as it has a broad spectrum of activity against different species, nevertheless it is non ovicidal. ( Taylor, Coop et Al. 2007 ) . In both the host and nematode the drug acts as a depolarizing neuromuscular blocking agent. ( Urquhart 1996 ) . This means the parasite is paralysed and expelled fleetly. As the host is targeted besides, side consequence can include hyperactivity for a short period after dosing and increased cellular activity. Unlike benzimidazoles, imidazothiazoles can hold a toxicity effects from nervus ganglia stimulation. Death can happen in extreme over doses. Both pyrantel and morantel act as selective agonists, copying the action of acetylcholine. This consequences in a speedy palsy and ejection of the worms via gut vermiculation. ( Taylor, Coop et Al. 2007 ) . Imid azothiazoles tend to hold a short action and can be used against other helminth groups. The last group of vermifuges used for nematode control in sheep, are the avermectins/milbemycins, besides known as macrocyclic lactones. Avermectins include ivermectin, doramectin, eprinomectin and selamectin, where as milbemycin and moxidectin make up the milbemycins group. The two bomber groups differ in their construction make up but are both effectual against a wide spectrum of activity against roundworms and other arthropods. Even at low doses the drugs are good absorbed systemically remaining within the host for a figure of hebdomads after disposal. ( Taylor, Coop et Al. 2007 ; Urquhart 1996 ) . However due to this drawn-out life, it is indispensable that the animate being is withdrawn from nutrient production subsequent to any interventions, although eprinomectin can non be given to breastfeeding herd. The mechanism of this group is non wholly known but it is thought that they act on glutamate gated chloride conductance channels at the neuromuscular junction. ( Taylor, Coop et Al. 2007 ) . The overall consequence is flaccid palsy of the bodily muscualture, which in bend inhibits feeding actvity. Increased use of any of the anthelminthic categories can take to a physique up of opposition. Resistance can originate within a nematode population, when the frequence of persons which can defy the action of the drug given, additions. The survival trait is so inherited by the roundworms progeny developing the opposition farther. Numerous signifiers of opposition depend on the manner of action of the drug. For illustration, side and cross-resistance where the choice for a drug occurs from holding the same or different manner of action of another. Multiple oppositions can come about when roundworms are opposition to two or more different vermifuges groups. ( Prichard, Hall et al. 1980 ) . Resistance normally is a consequence of an addition in the frequence of the anthelminthic, nevertheless, it can besides be selected when the drug is administered at a low frequence over a longer period of clip. ( Jabbar, Iqbal et Al. 2006 ) For illustration, it was found on the islands of Greece that sheep dosed merely two or three times yearly, still incurred opposition over a figure of old ages. ( Coles, Papadopoulos et Al. 1995 ) The rate at which the opposition builds up depends on several facets. The most important include the frequence of worms in refugia, the figure of of course immune worms within the untreated host population and the survival ability of the opposition worms when faced with a drug onslaught. ( Coles 2005 ) . Geneticss besides play a cardinal function in finding the rate of opposition. As with any trait if the cistron is dominant it will be passed on to progeny at a faster rate than if the cistron was recessionary. This has been seen within the opposition cistrons of Haemonchus contortus, against both levamisole and ivermectin, where they demonstrate either a recessive or a dominant nature, severally. ( Sangster, Redwin et Al. 1998 ; Le Jambre, Gill et al. 2000 ) When dosing animate beings, the drug should choose for the dominantly familial resistant worms intending the recessively familial resistant worms will last. This will cut down the rate at which opposition occurs. ( Prichard 1990 ) Many of the GI roundworms have built up either individual or multiple signifiers of opposition against the drugs used for intervention and control. The mechanism against each of the categories differs, due to the manner of action of the drugs themselves. As Haemonchus contortus and Trichostrongylus colubrifoemis are used to show the opposition of mechanism benzimidazole. The immune cistrons occur from two separate beta tubulin loci isotype-1 where allelomorphs are lost. ( Roos, Kwa et Al. 1995 ) There are a figure of trials that can be used to show opposition, runing from fecal egg count decrease trial ( FECRT ) to PCR. Trials can be specific to a category of vermifuges or used with any of the groups. ( Coles, Jackson et Al. 2006 ) . Trials fall three chief classs ; public presentation based, in vivo and in vitro. ( Jabbar, Iqbal et Al. 2006 ; Kenyon, Greer et Al. 2009 ) A combination of epidemiological and public presentation ratings can be utilised to observe anthelminthic opposition. Livestock weights can be used as indexs for worm loads, as weight addition diminutions if there is a heavy infection. This is seen with sheep infected with gastrointsetinal roundworms, particulary with lambs where weight falls prior to any clinical symptons. ( Coop, Sykes et Al. 1977 ) There are two methods used which rely on weight addition or loss. ( Kenyon, Greer et Al. 2009 ) . Although in New Zealand, Teladorsagia spp was found to hold developed less opposition to intervention, when the heaviest 15 % of lambs were elminated from dosing during the graze season. ( Leathwick, Miller et al. 2006 ) This implies that the heavier lambs are of course infected with the parasite from the grazing land, and accordingly weight addition lessenings. As parasites are exposed less to the anthelminthic, opposition patterned advance slows. To quanitify this techneque, energy deposition and consumption are calucated.Environmental factors are taken into history when ciphering the energy. ( Greer, Kenyon et Al. 2009 ) As environmental factors are taken into history, intervention efficaciousness values can be applied throughout the twelvemonth, within and out of the graze season.Individuals are so predicted their weight addition and intervention is given whether or non weight addition is expected. ( Kenyon, Greer et Al. 2009 ) . In vivo trial are any which require the carnal itself and include fecal egg decrease trials, critical vermifuges trials and the controlled vermifuges efficaciousness trial. ( Jabbar, Iqbal et Al. 2006 ) FECRT can be used on any of course infected carnal casting fecal roundworm eggs, against any anthelminthic. Faecal egg counts are taken prior to intervention and once more one time intervention is administered. A comparing can so be made to find whether the egg counts are affected by the anthelminthic. ( Coles, Bauer et Al. 1992 ) . The clip between disposal and mensurating the fecal egg count can change, depending on the drug used. For illustration if levismisole or morantel are given the FECRT should be conducted seven yearss after intervention as the drugs are fast moving. However if a benzimidazole is administered, egg counts should be performed eight to ten yearss after the intervention. This group of drugs along with the avermectins/ milbemycins, has a impermanent sterilising action on female worms intending the females can non bring forth eggs. ( Coles 2003 ) When an avermectin is administered the sheep should be left for about two and half hebdomads. If all three groups are t ested for at one time attention demands to be taken, as if the fecal counts are left until three hebdomads after intervention so larvae caught station disposal may develop into mature grownups. ( Coles 2005 ) To number the figure of existent eggs found in sheep fecal matters, the McMaster method affecting centrifuging and repairing slides, can be used, nevertheless a more convenient on-farm method has been developed. The FECPAK uses a system of thining the fecal mixture and adding a salt solution, eventually being sieved to be so fixed on the slide. The technique tests nematode eggs to a sensitiveness of 30 eggs per gm, although, it is non every bit sensitive as the research lab method. ( Coles 2003 ) . The cardinal advantage to this technique is that it non merely has an on-farm FECRT, but it works with all of the anthelminthic groups. ( Coles 2005 ) It can be besides used as an index of what type of anthelminthic flock government should be practiced ( Leathwick, Waghorn et Al. 2006 ) .However, the trial merely reviews the figure of eggs found in fecal matters samples. The vermifuges efficaciousness will non be an accurate representation of the true figure of worms, including larvae, populating in the host. ( Jabbar, Iqbal et Al. 2006 ) . In most species of roundworms this is the instance, although it has been found that Haemonchus contortus bears a strong correlativity between its fecal egg counts and true worm loads. ( Sangster, Whitlock et Al. 1979 ; Chalmers 1985 ) . In countries where multiple species of worm infections occur, the high worm and egg production of Haemonchus contortus can mask Numberss of other worms such as Teladorsagia circumcincta, which has a lower egg produ ction rate but still may hold a degree of opposition. ( Kenyon, Greer et Al. 2009 ) . Resistance ideally needs to be detected at the early phases to avoid it distributing across the flock population. ( Sangster and Gill 1999 ) Although FECPAK is available on the market, most FECRT require research lab analysis, so the consequence takes clip to be evaluated. ( Kenyon, Greer et Al. 2009 ) . Within the period in which the husbandman may be expecting the analysis, the flock may endure if the worm load is big. The husbandman will non may non merely lose stock but the finicky costs of intervention may increase. Resistance is detected if either of the followers are established ; the 95 % confident interval degree peers or is less than 90 % , and if the egg count decrease is less than 95 % . ( Coles, Bauer et Al. 1992 ) . The critical anthelminthic trial has a strong advantage of that, although few animate beings are used, they act as their ain control. The process compares the figure of worms present station intervention to the figure in the animate beings post slaughter review. Faecal samples are taken for a lower limit of four yearss after the drug is administered. Both the residuary worm Numberss and the efficaciousness per centum are so determined. ( Gordon 1950 ) . The chief disadvantage of this trial nevertheless, is that it the worm Numberss can merely of all time be estimated as roundworms found in the GI piece of land of sheep undergo a grade of digestion. ( Reinecke 1962 ) . The trial is both clip and labor consuming, intending the consequences are non instant for finding the needed intervention. ( Johansen 1989 ) . The last in vivo trial, which can find anthelminthic opposition, is the controlled anthelminthic efficaciousness trial. Animals here are unnaturally infected with roundworms that are suspected of being opposition to specific drugs. The anthelminthic activity of all phases of the parasite development can be evaluated by butchering the hosts at different intervals post-treatment. ( Reinecke 1962 ) . Resistance is found when the figure of worms, which survived the intervention, is greater than a 1000 or if the decrease figure is less than 90 % . Normally ranges of anthelminthic doses are used, intending dose-response parametric quantities can be determined. Although assorted parasites can used with this technique, in bred lines of animate beings are normally used to extinguish any single prejudice. A major disadvantage with this trial is that it requires skilled personal to execute station mortem scrutiny, connoting that it can non be routinely used for sensing of anthelminthic opposition. ( Johansen 1989 ) . In vitro techniques are one those conducted in the research lab. These techneques exploit physiological traits of the roundworm such as growing, motion and development. ( Conder and Campbell 1995 ) . Compared to in vivo techneques, in vitro are cheaper, utilizing fewer animate beings and chemicals to prove are big sample. Non-bias reproduction can be performed, with hastiness, to measure the efficaciousness and opposition of drugs. However in general, labaoraory surveies are do non resemnle field conditions, intending the drug may interact otherwise with the parasite and host. ( Sangster and Gill 1999 ) . The egg hatch trial is the most common in vitro trial, specifically observing the opposition of benzimidazoles. ( Coles, Bauer et Al. 1992 ) . There are legion methods which can be used, all trusting on the vermifuge s ovicidal trait and for the eggs to hold a grade of opposition. The development of the eggs is depressed within the early phases of development due to the larvae going non-compliment to the anthelminthic ovicidal action. ( Lejambre 1976 ) . The technique was foremost illustrated by Le Jambre ( 1976 ) . Fresh sheep fecal matters incorporating roundworm eggs are collected. This is one of the disadvantages, as when applied on the field, fecal samples may non be excreted within three hours, which is what defines a sample as fresh. If this is non executable samples may be stored anaerobically. ( Coles, Bauer et Al. 1992 ) . A cardinal advantage of this method if that merely one fecal sample is needed. ( Jabbar, Iqbal et Al. 2006 ) . Once the facecal samples are collected, egg are deposited into welled home bases and a graduation of anthelminthic concentrations are added. Using assorted concentrations prevents more than 50 % of the eggs hatching. Eggs are than incubated and so put through a procedure of I lavation. The dosage needed to kill 50 % of the eggs is so calculated. ( Coles, Bauer et Al. 1992 ) . The discrimintating dosage is can besides be calculated. This prevents 99 % of the eggs hatching and hence any eggs that do hatch are immune to the drug. 0.1mg per milliliter of thiabendazole has been found to be the discriminating dosage for Haemonchus contorus, T. Circumcincta and Trichostrongylus. ( Coles, Jackson et Al. 2006 ) . Although merely one sample of fecal matters is needed, undeveloped eggs are needed for the nosologies. ( Coles and Simpkin 1977 ) Newer benzimidazoles, such as fenbendazole, have a lower solubility, which reduces their ovicidal action. The egg hatch trial, hence, can non be used to research opposition of some specific drugs. This can present as a job as the new found benzimidazoles are normally used in pattern. ( Lacey and Prichard 1986 ) . Although this is a important disadvantage of the method, thiabendazole ( Jabbar, Iqbal et Al. 2006 ) , which can be used in the trial, has demonstrated to hold side opposition wth other benzimidazoles, so any opposition found in thiabendazole may be applied to other drugs of this category. ( Martin, Anderson et Al. 1985 ) Another concern of the egg hatch trial occurs during the numeration of the eggs. Larvae, embryonated eggs and simple larvae are counted to cipher about the effects of the drug. Merely a little proportion of the embryonated eggs of the vulnerable roundworms, hatched. The proportion that hatched decreased when the drug concentration increased. However, when looking at the immune strains, the bulk of the eggs hatched. When the per centum of the eggs that hatched is calculated, the opposition ratio will be lower, when compared to when the larvae or embryonated eggs are counted. The ratio of opposition is the egg count opposition to the egg count susceptibleness. ( Johansen 1989 ) Although the trial is fast, taking merely one to three yearss, European research lab egg hatch testings, frequently result in assorted decisions being drawn from the same population of Haemonchus contortus. The analysis established that the H2O samples, cleaniness and trying method used, differed. ( Coles, Jackson et Al. 2006 ) . Egg hatch trials are besides used utilizing levamisole, where the figure of hatches are counted to use any differences between both immune and vulnerable strains. Their rate of recovery from paralysed unhatched larvae to hatching is measured when exposed to the drug. ( Dobson, Donald et al. 1986 ) The check is faster than for benzimidazoles ; nevertheless, the levamisole trial is more labour demanding. ( Johansen 1989 ) . Both FECRT and the egg hatch trial merely demonstrate anthelminthic opposition when any bar methods are excessively late to implement. ( Jabbar, Iqbal et Al. 2006 ) . The larval palsy trial is used against levamisole and morantel opposition. ( Martin and Lejambre 1979 ) The technique involves L3 phase larvae being incubated within assorted dilutions of the vermifuges. Assorted reappraisals have been reported about this method, proposing both failures and success. The chief issue of concern is the dependability of th consequences and their relationship to the age of the larvae. ( Geerts, Brandt et Al. 1989 ; Jabbar, Iqbal et Al. 2006 ) This trial is known to back up in vivo method, as it is more sensitive than either FECRT and EHT, observing opposition in less than 10 % of worms. ( Dobson, Lejambre et Al. 1996 ) Another in vitro trial used to show anthelminthic opposition is the larval development check. This trial can measure a wider spectrum of categories integrating macrocyclic lactones, nevertheless it does necessitate more clip and labor so antecedently described trials. The trial involves exposure of the L1 larvae to assorted diltutions of drugs within agar home bases. The larvae are left to develop until the L3 phase is reached, and so later measured. ( Jabbar, Iqbal et Al. 2006 ) . When proving an infection with multiple roundworm species, the different species can be detected easy with this technique compared to other methods discussed. ( Johansen 1989 ) A more specific trial used in the sensing of anthelminthic reistance within Trichostrogylid is the grownup development trial. Unfortunately there are restrictions within the methodological analysis of the technique and so advancement is resitricted. ( Jabbar, Iqbal et Al. 2006 ) The larval motility trial is used to place opposition within the two major categories of vermifuges, but fails to effectual with the sensing of levamisole opposition. ( Sangster, Riley et Al. 1988 ) . Again as the trial used complexed equipment, it can merely be applied to the labaortory and non used out in pattern. ( Conder and Campbell 1995 ) . The technique involves dosing the roundworms with dilutions of the anthelminthic drug, followed by the percebtage of the paralysed L3 phase larvae being calculated. Normally both a known susceptible and immune strain of the parsites are used for a comparing to be deduced. ( Johansen 1989 ) A cardinal advantage of this technique is the usage of L3 larave. These be acquired easy in big Numberss from faceal samples and abled to be stored for longer periods of clip. Unforuntaly the trial has some major drawbacks. The check is extremely dependent on clip, whereby any miscounted larvae can non be kept for future computations one time out of storage. ( Johansen 1989 ) . As the benzimidazole s mechanism is to adhere to beta tubulins, a technique has been developed to prove resistant utilizing this alone belongings of the drug. From either the grownup parasites, morbific larvae or egg, a rough infusion of tubulin is produced. Titrated benzimidazole ( with label ) is added, until an equilibrium is reached. ( Lacey and Snowdon 1988 ) . Charcocal is used to pull out the drug in its free signifier, go forthing the bound drug to the tubulin infusion withn the solotuion. An appraisal is so made with a complex liquid spectrometer. As predicted the tubulin from immune strains binds to fewer drug compounds than the more vulnerable strains. ( Johansen 1989 ) . An advantage of the tubulin bindning check, is that it relies on the biochemical traits of the drugs s mechanism. Compared to other in vitro techniques it used in a more dependable comparing with field based trials, every bit good as holding a speedy turnaround from the gathered sample to the consequence. However complexed research lab machines are still used by skilled workers, together with radioactive isotopes, necessitating specialised safety installations. ( Johansen 1989 ) . PCR, otherwise known as polymerase concatenation reaction trials, have been developed for benzimidazoles chiefly but research is trying to understand the molecular mechanism for levamisole and macrocylic lactones. To come on into any of the trial discusses above, a PCR will hold been conducted against the particlaur drug in usage. ( Coles, Jackson et Al. 2006 ) . First, for a PCR trial to be conducted, DNA is extracted from the larvae. A specific concentration is needed per micro bath, as any varioation between them may take to incorrect DNA sequences being developed. For the peculiar acknowledgment of the benzimidazole, two consecutive PCRs are ran on the isotope beta tubulin, magnifying the Deoxyribonucleic acid. The species of parasite is so established by utilizing the this fragment analysis. For illustration Haemonchus contortu or T. Circumcincat may be found. This is a cardinal advantage of PCR, as with other trial the visual aspect of the species is used to set up its individuality PCR, hence used an accurate method of placing the species by its genome. ( Coles, Jackson et Al. 2006 ) . Following this designation, in entire four sets of primers are used, two being allele non-specific, the others being allele particular. Fragments are so produced, separating between either resistant or vulnerable homozygote strains. ( Coles, Jackson et A l. 2006 ) . When four primers of benzimidazole opposition were used, positive consequences were obtained with the parasite T.circumcinta. Similar consequences were found utilizing merely three immune primers with H. Contortus and T.colubriformis ( Silvestre and Humbert 2000 ) . When used in the field, the gathered sample will frequently be a assorted population of roundworms. The frequence of which the allelomorphs will happen will straight depend on the fraction of the roundworm within the entire population. ( Coles, Jackson et Al. 2006 ) . The trial proves that both the homozygote and heterozygote allelomorphs are vulnerable to the drug, connoting that opposition arises from homozygous of the tyrosine. As benzimidazole opposition in Trichostrongylus is to a great extent researched utilizing this trial, it has been established that the resisatance occurred due to a mutant of phenylalanine to tyrosine of the isotope 1 cistron encoding for the beta tubulin. It was utilizing this footing that that the usage of PCR to observe drug opposition in gastro intestinal of sheep Cam about. Although in theory, this appears to be the most accurate, the mutants of parasite doing the drug resistant must be known. The greater the possibility of nematode mutating to go more residtant, such as within sheep, the more inaccurate PCR will go. Unfortunately, nevertheless, in some instances this is the lone opposition detection technique for some benzimidazoles. Compared to other trial available on the market, PCR is an expenisive trial to use to observe on-farm resisatnce. ( Coles, Jackson et Al. 2006 ) . Kwa M.S. , Veenstra, J.G. and Roos, M.H. , 1994. Benzimidazole opposition in Haemonchus contortus is correlated with a conserved mutant at amino acid 200 in B A ; z.eth ; -tubulin isotype 1. Mol. Biochem. Parasitol. 63, pp. 299-303 The most common molecular mechanism that confers BZ opposition in trichostrongyles in little ruminants involves a phenylalanine to tyrosine mutant at residue 200 of the isotype 1 b-tubulin cistron ( Kwa et al. , 1994, 1995 ; Elard et al. , 1996, 1999 ) . However, in add-on a similar mutant at codon 167 may be involved in BZ opposition in roundworms ( Prichard, 2001 ; Pape et al. , 2003 ) and there could be other specific mechanisms. Although ailing efficient, non-specific mechanisms such as drug conveyance may besides confabulate opposition ( Xu et al. , 1998 ; Kerboeuf et al. , 1999 ) and could even confabulate advantage to a worm when a fresh drug is introduced. The cardinal issue is that merely when a diagnosing based on utilizing pooled larval DNA samples can be obtained will it be possible to convey molecular immune proving to routine usage. Testing of representative Numberss of individual phases is prohibitively expensive. Besides the available molecular trials chiefly address opposition in species where the job is widespread and in some instances may be excessively common to warrant testing. Conclusion-8.3. coles-The sensing of anthelminthic opposition in roundworms of veterinary importance Larval development trial There are presently two larval development trials of involvement, the liquid based trial described by Hubert and Kerbouf ( 1992 ) and the agar based trial of Gill et al. ( 1995 ) . Is one easier to utilize than the other? Whilst they appear to work for BZs and LEV in ovine and equid roundworms they do non look to work with MLs and have non been produced for usage with bovine roundworms. As for the EHT big sums of informations demands to be collected before a SOP and its readings can be agreed. In peculiar the relationship needs to be determined between these standardised trials and the FECRT. Although the LDT will work for BZ opposition, it appears non to be as Chalmers, K. ( 1985 ) . Detection of Benzimidazole Resistant Nematodirus-Spathiger. New Zealand Veterinary Journal 33 ( 4 ) : 53-53. Kales, G. ( 2003 ) . Strategies to understate anthelminthic opposition in big carnal practice. In Practice 25 ( 8 ) : 494-499. Kales, G. C. ( 2005 ) . Anthelmintic resistance-looking to the hereafter: a UK perspective. Research in Veterinary Science 78 ( 2 ) : 99-108. Kales, G. C. , C. Bauer, et al. ( 1992 ) . World-Association-for-the-Advancement-of-Veterinary-Parasitology ( Waavp ) Methods for the Detection of Anthelmintic Resistance in Nematodes of Veterinary Importance. Veterinary Parasitology 44 ( 1-2 ) : 35-44. Kales, G. C. , F. Jackson, et al. ( 2006 ) . The sensing of anthelminthic opposition in roundworms of veterinary importance. Veterinary Parasitology 136 ( 3-4 ) : 167-185. Kales, G. C. , E. Papadopoulos, et al. ( 1995 ) . Tubulin, Resistance and Worms. Parasitology Today 11 ( 5 ) : 183-184. Kales, G. C. and K. G. Simpkin ( 1977 ) . Resistance of Nematode Eggs to Ovicidal Activity of Benzimidazoles. Research in Veterinary Science 22 ( 3 ) : 386-387. Conder, G. A. and W. C. Campbell ( 1995 ) . Chemotherapy of Nematode Infections of Veterinary Importance, with Particular Reference to Drug-Resistance. Advances in Parasitology, Vol 35 35: 1-84. Coop, R. L. , A. R. Sykes, et al. ( 1977 ) . The consequence of a day-to-day consumption of Ostertagia circumcincta larvae on organic structure weight, nutrient consumption and concentration of serum components in sheep. Res Vet Sci 23 ( 1 ) : 76-83. Dobson, R. J. , A. D. Donald, et al. ( 1986 ) . An Egg-Hatch Assay for Resistance to Levamisole in Trichostrongyloid Nematode Parasites. Veterinary Parasitology 19 ( 1-2 ) : 77-84. Dobson, R. J. , L. Lejambre, et al. ( 1996 ) . Management of anthelminthic opposition: Inheritance of opposition and choice with relentless drugs. International Journal for Parasitology 26 ( 8-9 ) : 993-1000. Geerts, S. , J. Brandt, et al. ( 1989 ) . Reliability and Reproducibility of the Larval Paralysis Test as an Invitro Method for the Detection of Anthelmintic Resistance of Nematodes against Levamisole and Morantel Tartrate. Veterinary Parasitology 30 ( 3 ) : 223-232. Gordon, H. M. ( 1950 ) . Some facets of parasitic gastro-enteritis of sheep. Aust Vet J 26 ( 4 ) : 65-72. Greer, A. W. , F. Kenyon, et al. ( 2009 ) . Development and field rating of a determination support theoretical account for anthelminthic interventions as portion of a targeted selective intervention ( TST ) government in lambs. Veterinary parasitology 164 ( 1 ) : 12-20. Jabbar, A. , Z. Iqbal, et al. ( 2006 ) . Anthelmintic opposition: the province of drama revisited. Life Sci 79 ( 26 ) : 2413-31. Johansen, M. V. ( 1989 ) . An rating of techniques used for the sensing of anthelminthic opposition in nematode parasites of domestic livestock. Vet Res Commun 13 ( 6 ) : 455-66. Kenyon, F. , A. W. Greer, et al. ( 2009 ) . The function of targeted selective interventions in the development of refugia-based attacks to the control of GI roundworms of little ruminants. Veterinary Parasitology 164 ( 1 ) : 3-11. Kenyon, F. , A. W. Greer, et al. ( 2009 ) . The function of targeted selective interventions in the development of refugia-based attacks to the control of GI roundworms of little ruminants. Vet Parasitol 164 ( 1 ) : 3-11. Lacey, E. and R. K. Prichard ( 1986 ) . Interactions of Benzimidazoles ( Bz ) with Tubulin from Bz-Sensitive and Bz-Resistant Isolates of Haemonchus-Contortus. Molecular and Biochemical Parasitology 19 ( 2 ) : 171-181. Lacey, E. and K. L. Snowdon ( 1988 ) . A Routine Diagnostic Assay for the Detection of Benzimidazole Resistance in Parasitic Nematodes Using Tritiated Benzimidazole Carbamates. Veterinary Parasitology 27 ( 3-4 ) : 309-324. Le Jambre, L. F. , J. H. Gill, et al. ( 2000 ) . Inheritance of avermectin opposition in Haemonchus contortus. International Journal for Parasitology 30 ( 1 ) : 105-111. Leathwick, D. M. , C. M. Miller, et al. ( 2006 ) . Drenching grownup Ewe: deductions of anthelminthic interventions pre-and post-lambing on the development of anthelminthic resistance. N Z Vet J 54 ( 6 ) : 297-304. Leathwick, D. M. , T. S. Waghorn, et al. ( 2006 ) . Selective and on-demand soaking of lambs: Impact on parasite populations and public presentation of lambs. New Zealand Veterinary Journal 54 ( 6 ) : 305-312. Lejambre, L. F. ( 1976 ) . Egg Hatch as an Invitro Assay of Thiabendazole Resistance in Nematodes. Veterinary Parasitology 2 ( 4 ) : 385-391. Martin, P. J. , N. Anderson, et al. ( 1985 ) . Resistance to Benzimidazole Anthelmintics in Field Strains of Ostertagia and Nematodirus in Sheep. Australian Veterinary Journal 62 ( 2 ) : 38-43. Martin, P. J. and L. F. Lejambre ( 1979 ) . Larval Paralysis as an Invitro Assay of Levamisole and M

Comparison of numbers of organisms In Coniferous And Deciduous Woodlands Essay Example

Comparison of numbers of organisms In Coniferous And Deciduous Woodlands Essay Example Comparison of numbers of organisms In Coniferous And Deciduous Woodlands Paper Comparison of numbers of organisms In Coniferous And Deciduous Woodlands Paper An experiment was done to find out whether there was a difference in the number of organisms in the coniferous and deciduous woodlands. A quadrat of 10m by 10m was used and co-ordinates 5,1 5,2 5,3 5,4 5,5 5,6 5,7 5,8 5,9 5,10 were used because these were exactly in the middle of the quadrat area. Ten samples of leaf litter and ten samples of humus was obtained from each woodland. In the laboratory tullgren funnels were set up, the samples were tested and the organisms were collected. A results table was made to record the numbers of organisms in. The results were displayed in graphs and tables. The graphs show the average number of each organism and the actual number of each organism in each of the woodlands. In the third graph five significant organisms have been picked out. This is because they have significant values and reasons for these values. The tullgren funnel was set up using a certain amount of the leaf litter that acted as a sieve that the organisms could fall through from the humus that was placed on top of the leaf litter. 20g of humus and 10g of leaf litter was used in the tullgren funnel because only a small amount was needed. A 100w bulb was used in both experiments (for each woodland). The organisms were driven, by the drying effect of the bulb, down the tullgren funnel and eventually they fell into the 30cm3 of ethanol. The organisms died but their bodies were preserved so that at the end of five days the different organisms in the ethanol and the larger organisms in the dried up leaf litter could be identified and recorded using a microscope and a dichotomous key. This method was used because it was the most reliable, and ensured that all organisms present were removed from the sample in the tullgren funnel. Some very small organisms that were not affected by the drying effect of the bulb were not counted. During the experiment predation between organisms were occurring, this was not accounted for. The average test and the t-test were used, because two averages were being compared and there were less than 25 unmatched organisms in each sample. The value of t = 5.524 was greater than the value given for 22 points of freedom so that the Ho (null hypothesis) was rejected and the alternative hypothesis was accepted. Therefore the assumption, that the number of organisms are greater in the deciduous woodland, can be made. So the number of organisms did differ in the deciduous and coniferous woodland. The decomposition rate in the deciduous woodland is faster because organisms such as the earthworm can survive in this environment, because this environment is more alkaline than the coniferous woodland, which is more acidic. If conditions are less acidic then organisms such as the earthworm can survive and continue the fast decomposition, keeping the surrounding environment more alkaline. This is a negative feedback effect. So the number of species was greater deciduous woodland, with the exception of Springtails and small spiders. This is because these organisms have adapted to the acidic conditions of the coniferous woodland. Hypotheses Null Hypothesis (Ho) there was no difference in the number of organisms in the two soils. Alternative Hypothesis (H1) there was a difference in the number of organisms in the two soils. The Aim The aim of this investigation is to compare the difference in numbers of invertebrates in the coniferous and deciduous woodlands when samples are taken from each. The samples taken will be tested, recorded and evaluations will be made. Prediction The data collected will show that a coniferous woodland will contain fewer of the organisms that have been selected for study than in the deciduous woodland, and also that the depth of leaf litter will be considerably more in the coniferous woodland than in the deciduous woodland. Evidence In the deciduous woodland where the experiment was done, many different species of trees were growing. These trees have large, thin green leaves, to absorb the maximum amount of sunlight available. When these leaves fall off the trees to the ground, detritivores such as the worm, start the chain of decomposition. Without the detritivores the saprophytes (bacteria) cannot continue the process, after the detritivores, of breaking down the complicated organic matter. These leaves have a large surface area for detritivores to start the process of decomposition. Decomposition occurs relatively quickly therefore the layer of leaf litter will be thinner. However, in the coniferous woodland where the experiment took place there was only one species of tree and that was the pine. The pine needles are long and thin which are thought to increase the surface area for the absorption of sunlight. This surface area is also where, when the pine needles fall to the ground, the detritivores start the process of decomposition. Because of the conditions in the coniferous woodland the detritivores take longer to decompose the leaf litter. Therefore if the rate of decomposition is slow, and the rate of the pine needles falling are fast, then there will be more leaf litter on the ground of the coniferous woodland than on the floor of the deciduous woodland. The exotic conifer grows at a faster rate than the native broardleaves. Because the conifer is exotic, there are few insects and birds associated with it and so the exotic conifer is useless for use by native organisms. Because conifers are planted as a monoculture they are easy to manage (i.e. planting, weeding, fertilising, etc). But each tree needs exactly the same amount of nutrients and water because they are of the same species. This causes a deficiency of nutrients in the soil and so fertilisers have to be used. This could eventually lead to pest epidemics and so pesticides may also be needed. When a monoculture is planted, all the trees are of the same age and so are easily managed because there is little variation in height. The conifer woodlands and forests are planted in straight lines and are therefore easier to manage. However, this arrangement looks odd and unnatural because trees in a deciduous woodland are not planted in this way. If the conifers are planted densely then this ensures reduced side branch growth and increased height (therefore increasing the value of the timber). If all the trees are removed at the same time there will be a drastic change of the landscape which may result in a large amount of soil erosion. Variables * Light intensity in the coniferous woodland = 3.5 * Light intensity in the deciduous woodland = 3.5 * Temperature in the coniferous woodland = 28oC * Temperature in the deciduous woodland = 27oC Syllabus Areas Climate (i.e. local and micro climates, vegetation, landuse, topography). The Lithosphere (i.e. soils, nutrients, acidity). Ecological Relationships (i.e. ecosystems). Soil (i.e. conservation, cultivation techniques). Mathematical Skills (i.e. plotting graphs, understanding graphs, etc).

Harley-Davidson in 2004..2011 Essay Example | Topics and Well Written Essays - 1250 words

Harley-Davidson in 2004..2011 - Essay Example The global market consumers consider all the factors while purchasing the motorbikes because the motorbikes in most of the countries are used by means of transport or the consumers who does not afford the cost of maintaining car: The motorbike industry of US is different from the international market because the US consumers do not use the motorbikes by means of transport. So US consumers do not consider all the above factors except superior quality. Every country has its own economic conditions that are different from the other country. In motorbike industry of under developing countries the consumers consider these factors: cheap in cost, average in quality, fuel efficient and spare parts available at cheap prices. And in the developed countries the focus of the consumers on superior quality, innovative features and designs etc. the economic conditions of a country creates a big difference in the consumer preferences. 2.1-The motorbike industry is growing very fast for the last two decades and now the total number of motorbikes in the world is around 200 million. It’s a very huge market with a huge growth every year. Many bug multinational entering in this fast growing market because in the under developing countries motorbikes is used as a means of transport and in developed countries it is used with a broad perception. Harley Davidson associates its brand image with life style of customers. Its market is increasing because today’s consumer associate it self with the product’s characteristics to build its personal image as a products image. This trend makes the market of Harley Davidson more effective and appealing. Harley Davidson is most selling motorbike brand in US market and containing a highest market share in the US motorbike industry. The sales and the market share of Harley Davidson in the US motorbike industry

Write an analysis of 2000 words of one of the following Hong Kong Essay

Write an analysis of 2000 words of one of the following Hong Kong films - Essay Example Moreover the martial art of Kung Fu widely acclaimed in China is found to act as a common stunt piece for many Chinese, Japanese and Hollywood films. Further observation made suggests that the Chinese martial art form, Kung Fu has earned a figure statement. With Kung Fu mostly masculine bodies with high power muscles earning a spectacular vision is mostly tied to. Thus, the martial art of Kung Fu has been associated to a body genre accompanied by heavy sound effects like shrieks and thuds. To this extent, it is found that the Chinese martial arts films are the products of a culture mix. (Hunt, 2-3). The martial arts used in the Chinese film industry in the late 1960s emanated from the tactics used by the Samurai form of Japanese Martial Art. Research made suggests that in the earlier periods of Hong Kong film industry the Chinese form of martial art drew a fictional significance to that of the western action films. Moreover it was found that the Kung Fu form of Chinese martial art was blended with other cinematic instruments such as comedy, stunt and action filled antics. Even it is observed that film stars who were previously well known for their martial art skills now using less of martial art skills and focusing on showing stunts and antics. The level of stunts used in the Hong Kong action films owes their contribution to the effect of Chinese Opera on the fighting stars. However, it is recognized that still the fighting choreography has a close resemblance to the traditional martial arts form. The Kung Fu form of martial art finds its connection to the Southern part of the Chinese republic. Northern China was more concerned with the advent of sword fighting techniques used in action films. However, the use of Kung Fu in the Hong Kong action films has helped the cinemas earn a global repute in a short span of time. The Kung Fu films

Evaluation Essay Example | Topics and Well Written Essays - 500 words - 3

Evaluation - Essay Example While observing the speeches of Obama, we see him as possessing the first and foremost quality of an eloquent orator as mentioned earlier. Another notable feature of Obama is that he is always energetic and confident during his speeches that the long schedules or programs never did tire him. One dominant feature found in Obama’s speech is his ability to pause wherever necessary and resume the speech after observing or studying the audience. His style is identifiable when he began his Democrat Primary Victory Speech on 3rd June, 2008. The beginning, â€Å"Tonight, after 54 hard-fought contests, our primary season has finally come to an end† (Democrat Primary Victory Speech, 2008) justifies the former statement. Obama could also begin the speeches with striking words, though not often with quotations, and maintain the flow of words tinted with poetical lines. He has enough voice projection and voice modulation that can enchant people to him. To conclude, one can infer tha t Obama possesses the notable features of a good public speaker. An evaluation of McCain’ as a public speaker reveals that he is no less than Obama as a talented orator. He could also raise number of people, though he could not win American Presidency Elections against Obama. The outstanding feature of McCain’s speech is that he was motivational that he tried his best to motivate the audience. His words â€Å"Do not yield. Do not flinch. Stand up. Stand up with our President and fight. Were Americans. Were Americans, and well never surrender. They will† (McCain, 2004) are capable of stirring the minds of the people. Like, Obama, he also would acknowledge that his knowledge was limited, if he was not proficient in a particular topic. During his speeches, he tried to present the root cause of the existing problems in American Society as well as in economy. This is very clear when he said, â€Å"Americas most vital

Factors Effecting Erp Implementation In Smes Management Essay

Factors Effecting Erp Implementation In Smes Management Essay Information systems gained popularity as these automate all management related function that an organisation needed. Large organisations implement ERP information systems that integrate all data and processes together. With increase in popularity of SMEs (Small and Medium Enterprises) and their collaboration with large enterprises, SMEs needed an ERP system which at first can automate all of their business functions and secondly they can work with large enterprises. However their successful implementation in SMEs remains an issue. As SMEs are short of resources and financially weak so they need to install an ERP system successfully so that they can avoid chances of failure. For this reason this research has been conducted to critically analyse success factors of ERP adoption. Case studies will be selected and analysis has been made on them to find out the successful elements of their implementation. At last in conclusion a general frame work will be made to help SMEs to implement ERP system successfully. Background: Today the whole world has become a global village in which organisations are competing with each other to improve their productivity and generate profits. This is not generalised to only large organisations as it has been observed from last decade that small and medium size organisations are also taking part in this race (Chen, 2001). Organisations are moving fast to adopt a package that can help their management and functional needs. They require an Enterprise package that can fulfil their demands. ERP is the solution for the enterprises, in current case for small and medium size organisations. Enterprise Resource Planning (ERP) gained its popularity in 1990 as an integrated application. Its functionality is to integrate different functions together and provide a common database to users and departments, with many advantages more specific to reduced inventory and improved profits. ERP evolution starts in earlier 70s when manufacturing companies were using MPS (Master Production Schedule) technique. Function of this technique was to specify the end or finished product that is required in planning period. This type of technique only did the production and scheduling of final product. Whereas manufacturing organisations required not only final product planning but they also needed planning and scheduling of raw materials associated with that final product. Therefore firms obtained MRP (Material Requirement planning) that can differentiate between final product, its parts and raw material. This technique performed production planning and inventory control in the manufacturing p rocess. Basic functionality of this system was planning and scheduling of manufacturing process. This technique became popular and in 1980s MRP systems were expanded and MRP II was introduced, it was not only production planning technique but it also integrated primary functions like (production, finance and marketing etc) into planning process. Because of this technique popularity and effectiveness in planning and production process organisations tend to move to this technique. In 1990s MRP II was further expanded into ERP (Enterprise Resource Planning). The main difference between ERP and MRP II is that ERP plans and schedule supplier resources by keeping customer service in mind (Chen, 2001 and Gupta, 2000). The purpose of the research is to identify success factors of ERP adoption in SMEs. Researches done in this area were deficient of some of the key points. From last couple of years research has been conducted to critically identify success factors of implementing ERP in SMEs. (Kale et al, 2010) did study in identifying success factors of Indian SMEs and their research was based on both qualitative and quantitative. (Snider et al, 2009) studied on five Canadian SMEs but some of their critical success factors lack cultural issues. (El Sawah et al, 2008) and (Woo, 2007) both did research in SMEs, in which they covered only one country and further they intended to enhance their research by taking more SMEs of different countries. (Woo, 2007) explained in study that if cultural differences were given then considered success factors can be same to case studies in China and case studies of Western organisation. (Doom et al, 2010) used Belgian SMEs to research success factors. (Muscatello et al. 2003) did their research on four US manufacturing companies but the companies they choose were linked to large organisations and had annual revenues more then SMEs .(Loh and Koh, 2004) carried out their research in UK and their target was SMEs, they conducted interviews and distributed questionnaires. Their research is found to be more competent as compared to others but still they did not cover demographic issues.(Yusuf et al, 2004) conducted their research on Rolls Royce and found out answers of few success factors. From above studies it is obvious that most of the work has been done in large organisation and little researches were carried out on SMEs. Although, those studies considered SMEs for the research but covered only one region and were short of justification that how success factors of some specific part of world could be implemented in rest of the world. Key issues in successful implementation of ERP Key issues are the problems that arise during the implementation process. There are lot of problems that can affect ERP implementation process in SMEs which are detailed as below (Chen, 2001). Cost is one of the main issues that can fail ERP implementation. As ERP package requires huge finances and companies fail to successfully implement ERP package so they find it difficult to continue with their project. To choose right ERP package is another issue that SMEs have to take into account before implementation. Hershey Food Corp accounts SAP for their failure so choosing right ERP package is a big issue. ERP in SMEs requires some time complex customization because it focuses mostly on corporate giants. So customization is another big issue that can effect ERP implementation. Another main issue is analysis, which projects are failure and which are successful. Project failure and success all depends on judgment and analysis. Fox Meyer as mentioned below, states that their ERP systems did not fulfil their functionality and they marked that project as failure. It is explained in detail in literature review section. Likewise some enterprises termed their project failure because of cost. Project can be termed as success if they meet these criteria. It should be delivered on time It should meet project cost The project should deliver the functionality which that organisation wants. Research aim and objectives The main aim of this study is to propose a frame work for effective implementation of ERP in SMEs. This requires in depth study of literature review and case studies to critically evaluate success factors. The research will be based on the following research question: What are the key issues and problems being faced in the successful implementation of the ERP in small and medium enterprises (SMEs)? To what extent the ERP software contributes to the success factors in SMEà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s? In order to answer the above stated research questions the following stages will have to be achieved: To review and carry out in depth analysis of literature review while focal point will be ERP adoption. Critically analyse and identify success factors from different case studies. Match and analyse success factors of literature review with the case studies Develop a frame work of success factors which can help in implementing ERP successfully for Small and medium size organisations regardless of their region and cultural issues. SMEs case studies will be taken who have generally less level of employees. Case studies will be taken from different regions so that more in depth analysis will be done and cultural and demographic issues will be covered in that. This point is explained in much more detail in method of analysis section. Companies who have successfully implemented ERP application will be considered. Literature review According to (Snider et al, 2009) ERP uses common online database whose functionality is to share common database among users and enterprise functions. ERP is an integrated information system that is composed of information system and managerial thinking. One of its core purposes is to integrate all the dependent and independent information systems together and optimise systems performance. ERP system comprises of a database which is online and shared, an application with an integrated interface which means different interfaces are incorporated into one interface. (AL Mashari et al, 2003). ERP achieved its level of popularity in large manufacturing enterprises in 1990s. Large enterprises implemented it to automate their functions and to integrate all processes and data together. On the other hand as SMEs were getting popularity so after implementing ERP systems in large organisations ERP vendors now moved towards SMEs. There are many factors that can encourage SMEs to accept ERP systems. Poston and Grabski (2001) believed there are certain factors that motivate SMEs to adopt ERP systems: It can reduce cost as computer systems increases the efficiency process It can make decision making process accurate. (Oliver and Romm, 2000) suggested these reasons for ERP adoption in SMEs: Data and processes integration Avoid critical business risk Improvement of ongoing business operations. ERP adoption in SMEs is a challenging task especially when cultural issues arise. Cultural issues can occur at organisational values, means it can impact organisational structure and management or at individual value where it can impact how job works and how employees will conduct themselves if they belong to certain culture. (Straub et al., 2001). Developing countries face many problems when they use western technologies from developed countries. ERP encapsulates best business reusable practices in it. For this reason it became a demanding technology that it can use (Sawah et al, 2008) outlined cultural issue to be an important factor responsible for high demand of ERP in SMEs. With these motivational factors that attract SMEs to adopt ERP there is terrible side of this adoption as well where many ERP enterprises fail to adopt ERP systems. Below mentioned are cases of large enterprises but small and medium size enterprises can learn lesson from them by not to adopt that type of implementation. Fox Meyer Drug, a multi billion pharmaceutical company which files for bankruptcy and they blamed ERP system for their down fall. In its case, problems in ordering system leaded as system generated excessive orders more than demand which lead company to down fall. Renowned companies like Dell scrap their mega expensive project as they found system inflexible for their business. These are not only two examples of ERP failures but many other companies like Hershey, Boeing, Dow chemical etc faced same situation (Chen, 2001). In all these companies ERP systems leaded to failure and this was due to not having proper planning before installation. Above mentioned companies a re all large organisations whereas in case of small and medium size organisations, these can not bear the cost of ERP systems failure. This leads this research to critically analyse and find out the success factors in ERP adoption so that SMEs can avoid these failures. Difference Between SMES and Large enterprises: Significant amount of differences can be noticed between large and SME organisations. SMEs have informal structure and culture, their top management are found to be involved in day to day activities (Mintzberg et al., 2003,) while large organisations have structured departments and processes and their top management is not involved in daily activities (Buonanno et al, 2005). At the same time SMEs have limited resources in terms of research development, finance, human resource with limited clients and operates only in small scale (Kale et al, 2010). Due to these limited resources they find it difficult to implement projects that can be reengineered (Mc Adam, 2002). Besides these limited resources they are generating profit very well and for this reason many multinational companies in recent years collaborated with SMEs which have ERP systems installed in them. This collaboration made SMEs to adopt ERP package so that they can operate in parallel with these organisations (Rao, 2000). The major factor which can affect SMEs more as compared to large organisation is the cost as their limited resources donà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢t allow them to bear high cost of implementation. This is one of the main reasons that SMEs do not want implementation to be unsuccessful. Large organisation can somehow bear the cost as large number of stakeholders bank credits etc but SMEs do not have enough resources. (Mabert et al, 2003). This research is conducted so that it can help SMEs to implement ERP successfully. Proposed research method Most of the researches conducted are in large organisations and only few of them were for SMEs. Out of these researches some used only one case study while some used different case studies and their research method remained different as well because they used questionnaires and interviews to find out success factors. After brain storming and critically analysing previous literature review I decided to use the case study approach. For this reason I decided to identify critical success factors in SME while using multiple case studies. (Stuart et al, 2002) suggested that using case study is the best approach when previous research does not find to be inline with new context while taking multiple case studies can provide even more in depth analysis and portray clear picture of critical analysis(Snider et al, 2009). In case of our research qualitative analysis will be used. First thorough literature review will be studied by means of online journals, electronic books etc. It will help to find previous critical success factors of ERP adoption in SMEs. To give practical edge to research eight different case studies will be searched and from them critically analysis will be done to find out success factors of successfully implementing ERP project. These case studies are selected with relevance to the project title and literature review. They will provide in depth analysis of ERP adoption success factors. With the help of literature review and case studies a framework will be formed of successfully implementing ERP project. Method of analysis For this research case study analysis will be used. Data will be collected from previous research that has been done in this sector and also from small and medium size enterprises that have implemented their ERP application successfully. Case studies will be collected from different parts of the world so that no demographic issues can affect our final framework of success full factors. Then final analysis will be done in between success factors of United Kingdom and rest of the world case studies to observe how much variation is there if different regions are selected. This will be the final analysis and framework of the critical success factors. Research Limitations: This study is limited to small and medium size organisations and in some cases some arguments can be taken from the large organization in order to clarify them. This research is self explanatory as it focuses in ERP adoption system of SMEs. In addition to this study concludes with the framework of ERP critical success factors which if SMEs follows can lead their implementation to success. A provisional Timetable Gantt Chart

The work

The goal of MapleBear schools is to establish an enthusiasm for learning and knowledge in young children that will serve as a foundation for future uccess in the education system and in I Premium327 Words2 Pages Welcome Speech Welcome speech Good Evening/Afternoon everybody! I am extremely honoured to have the chance to address you in this prestigious moment when our institution, VC Kumaran Memorial School celebrates its 33rd Annual Day today. This is so precious moment for us because aside from the fact this funced each and every inch of this stage, be so hesitant to come up here and speak.What I am about to do is absolutely Premium978 Words4 Pages Farewell Welcome Speech â€Å"Goodbyes are hard. It may be harder for the person leaving, but it's always hardest or the one being left behind. † Welcome everyone to this special occasion. This event is bitter-sweet occasion. It is very sad to say good-bye to our classes 10-A and 11-C who are ending their remarkable J Premium284 Wo rds2 Pages School Speech Dear Principal, Teachers, Parent and children a very good evening to you all.It is my pleasure to be here today. Being invited to be the Chief Guest at the must be one of the high points of any parent's life. I was a student many years ago and indeed it's a great honour to be abl Premium313 Words2 Pages School Speech by Chief Guest Draft speech of Mrs. D. Purandeswari, MOS-HRD (HE) as Chief Guest on the occasion of the Annual Day of the Rainbow Concept School, Mahaboobnagar, A. P on 9th February, 2007 at 5. 30 p. m.It gives me immense pleasure to be here this evening and to address the young students of the Rainbow Concept Sc Premium1998 Words8 Pages School Day discover as the colours of cultural feast unfold ! Premium308 Words2 Pages Annual Sports Day My School Sports Day Games are compulsory in every school as physical development along with mental development is essential. All students are not necessarily good in studies. Some are good in sports. Much to the Joy of each students the Sports Day is one of the major events in the school.

Marshall McLuhan’s Theory Essay

How might Marshall McLuhan’s theory of hot and cold media be used to explain the surge of interest in mobile technology, especially text and picture messaging? ‘Any invention or technology is an extension or self-amputation of our physical bodies, and such extension also demands new ratios or new equilibriums among the other organs and extensions of the body’, Marshall McLuhan in ‘Understanding Media’ (1964, p43). A comment which has possibly never been truer than when understood with regard to a mobile phone. McLuhan’s theories have recently been given new life with the onset of the Internet; however, they can also be usefully applied to the massive explosion of mobile technology. Given it is a medium which some may consider to be cool; its impact on society has been immeasurable. In today’s society it is difficult to meet a person between the ages of fifteen and fifty who do not own a mobile phone. Like televisions, it is the electronic accessory of the moment and it is advancing fast. Only five years ago text messaging was in its infancy and not all phones offered it; picture messaging was unheard of. Nowadays picture messaging is very much here and already the technology has moved towards video messaging. Some ‘mobile phones’ would be more accurately described as hand held computers as the telephony is only a fraction of its capabilities and often not even its main function. As with most mobile phones the main function consumer’s use is text messaging. According to McLuhan in ‘Understanding Media’ (1964) the advent of a hot explosive medium can cause drastic changes to politics and society. This can be seen in the effects that such technology has had on not only the telephone but the way people communicate in day to day life. However, when contrasted with a hot medium such as television or cinema, text and picture messaging are comparatively cool. They provide far less information and demand more participation from the receiver to fill in the gaps. Pictures received in messages are only small and very symbolic rather than detailed. There is also only limited space for text and language is often limited to abbreviations and annotation. Of course when compared to the standard telephone, mobile technology is considerably hotter, however, in order to stay within McLuhan’s theory, and for the medium to cause such a change in society, one would assume that the medium itself would need to be hotter. Such a change could be better explained and explored by the theories of Roland Barthes, particularly his writings on myths and semiotics. In a collection of articles entitled ‘Mythologies’ (1973) Barthes explores practical objects and their cultural meanings. Examining such objects as cars and haircuts he scrutinizes the ‘signifiers’ and ‘signs’ that they contain. ‘Barthes begins by making explicit the meanings of apparently neutral objects and then moves on to consider the social and historical conditions they obscure’ (McNeill 1996). He examined cars, comparing them to Gothic cathedrals, due to their uses over and above their basic functions. Cars carry status and tell a lot about the person who owns them (Barthes 1973). Such meanings can also easily be drawn from mobile phones. Far more useful than assessing whether or not they are hot or cold, deeper more analytical conclusions can be derived from Barthes’ methods. By exa mining the semiotics of the medium its position in society and culture and its effects could be estimated. In ‘Mythologies’ (1973) ‘he argued that myth was a mode of signification. He argued that in myth, the link between the signifier and the signified was motivated†¦so that a culturally constructed sign becomes a signifier, thus allowing what is signified to become naturalised’ (Hartley 2002). Hartley goes on to apply this theory to brand named sports wear and their attached meanings. Such an application could be used with mobile technology as not only are there many different mobile phones with different functions but many different brands. ‘Nokia’, in particular, as the apparently leading brand, has different model phones which contain different signifiers. Some appear fun and contain lots of features and gadgets; others appear sophisticated and look sleek and small. Others exist for practical purposes for uses who are less taken by mobile phone culture. Given the huge range of choice on offer, not just by ‘Nokia’ but all brands, the decision of which phone to purchase is an active one which takes serious contemplation. More can be said for a person who uses picture messaging. Society has not quite reached a stage where its considered a ‘necessity’ like text messaging so those who do use it are those who are particularly interested in the culture. More so as these phones and messages cost more it signifies how much money a person has or at least how they prioritise their spending. More meanings could be drawn from how often a person uses their phone and how many different people they know who can accept picture messages. Barthes also wrote about Text itself and its semiotics, arguing that words are strong and can be used as political weapons, as they have been in post World War II politics. He charts the beginning of the ‘moment of the text’ as 1968 (Hartley 2002). This seems to have affected the whole of society as people now talk to each other less, preferring to e-mail or send text or picture messages. McLuhan has commented on discourse and text. According to a website called ‘Marshall McLuhan: spinning the web of the future’, ‘specifically, McLuhan feels that the best way to convey information between two people is to maximize the use of the senses†¦[therefore] ancient oral civilizations appeared to have the greatest and most clear form of communication.’ That is not the written word, but the spoken. This has, however, been criticised by Miller (1971) who ‘disagrees with this assumption because he feels that humanity has evolved with technology a nd that this is not necessarily a bad thing. The reality is that further technological advances have given humanity the ability to communicate using mediums that are essentially extensions of the spoken word.’ McLuhan expressed concern over the effects of technology and its result in the loss of human identity, although he did not see it as a bad thing, it was something to be maintained and supervised. His concerns could be justified, however, in that nowadays people talk to each other less, preferring to communicate by the written, or typed, word. Concern should probably not to be so extreme as to fear the breakdown of society but it has seriously affected how we communicate and what we now spend our money on. According to McLuhan in ‘Understanding Media’ (1964) intense, hot media needs to be cooled off by our senses before it can be assimilated. Possibly then the appeal of the text and picture message is that they are easier to take in on a sensory level. They are quick, take only seconds to read and write and enough time is given to process the information between each message and response. Radio and cinema act as an assault on the senses demanding that attention be paid in order to take it all in, although fewer gaps need to be filled. In two-way communication, however, it allows the user time to consider their response and therefore reduces the risk of saying something which one may regret later. If we put together the two theories of McLuhan and Barthes it is possible to achieve composite critique of the phenomenon of mobile technology. Although much of what was written by, particularly McLuhan, has been excessively criticised, some disregard it all together, he makes some points which are useful when examining this area of contemporary media and technology. Using McLuhan to explore the more technical aspects of text and picture messaging, suggesting why it may be so popular. Due to its being hotter than a normal telephone it is likely to be the next step in technology and its convenience makes it so popular. Also fact that it is cooler than other direct forms of media and allows more time and less information for the brain to process ensures it is easier on our senses. Its very presence has caused an upheaval in our society and we have taken the next cultural and technological step in our ever progressing development. Barthes, on the other hand, we can look to for inspiration in analysing the cultural aspects of such communication technology and what it means. Using his methodology of examining mobile phones for signs and signifiers many conclusions can be drawn. As phones differ widely in style and in what features they contain each person can be judged on the phone they own, or the phone they wished they owned. Someone who has a phone that looks good, rather than containing many features is clearly saying something about the way in which they want to present themselves. Furthermore, a person who cares less about how the phone looks and more about what it does suggests something else. Most phones which contain more features, particularly a camera are usually larger and look less neat than those with fewer features. Phones that can be used to record short pieces of film or watch videos on are bigger still yet there are already people who own them. Such people may be looking for a phone with more f unctional value, as well as their having an interest in gadgets. That said, however, we can assume they gain intrinsic pleasure from showing a person what their, apparently less attractive, phone can do. We could also assume that such people wish to be ahead of technology and enjoy being one of the first to own such items. Near enough all young people own mobile phones and few would deny that they gain pleasure and enjoyment from them. ‘Texting’ has become a common, everyday form of communication; one that did not exist during the lifetimes of Marshall McLuhan or Roland Barthes and it can be assumed that neither would have anticipated this surge in technology. Both would express concern at its immense popularity as it risks people becoming less sociable and having less actual conversation. Another side to that argument, however, could be that it increases human interaction, it just takes place in a different way. People can now contact their family, friends and acquaintances much easier and faster. To send a text message to say ‘hello’ is far quicker and easier than making a phone call which could result in lengthy conversation. Whereas once a person may have decided against the phone call for that reason they will now send a text message. It is probably safe to say that, give n that human beings are an innately social species, and indulge in conversation for pleasurable as well as functional purposes that if what they desire is a conversation then that will be sought above a text message. It is hard to predict where society and culture will go with this ever increasing technological development. In the next year or so we can assume that videophone will become much more popular and that mobile phones will continue to develop into small computers than ‘phones’. Living in a century where convenience is emphasised and encouraged and our lives are busier it is likely that less face to face interaction will take place however with the help of the mobile phone we can avoid losing contact altogether.

Free Essays on Karl Pearson

The Mathematician, carried along on his flood of symbols, dealing apparently with purely formal truths, may still reach results of endless importance for our description of the physical universe. ~ Quoted in N Rose Mathematical Maxims and Minims (Raleigh N C 1988). Born: March 27, 1857 in London, England Died: April 27, 1936 in London, England Karl Pearson graduated from Cambridge University in 1879, then spent most of his career at University College, London. He was the first Galton professor of eugenics, holding the chair from 1911 to 1933. His book The Grammar of Science (1892), was remarkable in that it anticipated some of the ideas of relativity theory. It was wide ranging and attempted to extend the influence of science into all aspects. Pearson then became interested in developing mathematical methods for studying the processes of heredity and evolution. He applied statistics to biological problems of heredity and evolution. From 1893-1912 he wrote 18 papers entitled Mathematical Contribution to the Theory of Evolution which contain his most valuable work. These papers contain contributions to regression analysis, the correlation coefficient and includes the chi-square test of statistical significance (1900). His chi-square test was produced in an attempt to remove the normal distribution from its central position. Pearson coined the term 'standard deviation' in 1893. His work was influenced by the work of Edgeworth and in turn influenced the work of Yule. Pearson had a long dispute with Fisher. Pearson used large sample which he measured and tried to deduce correlations. Fisher, on the other hand, followed Gosset in trying to use small samples and, rather than deduce correlations, to find causes. The dispute was bad enough to have Fisher turn down the post of Chief Statistician at the Galton Laboratory in 1919 since it would have meant working under Pearson.... Free Essays on Karl Pearson Free Essays on Karl Pearson The Mathematician, carried along on his flood of symbols, dealing apparently with purely formal truths, may still reach results of endless importance for our description of the physical universe. ~ Quoted in N Rose Mathematical Maxims and Minims (Raleigh N C 1988). Born: March 27, 1857 in London, England Died: April 27, 1936 in London, England Karl Pearson graduated from Cambridge University in 1879, then spent most of his career at University College, London. He was the first Galton professor of eugenics, holding the chair from 1911 to 1933. His book The Grammar of Science (1892), was remarkable in that it anticipated some of the ideas of relativity theory. It was wide ranging and attempted to extend the influence of science into all aspects. Pearson then became interested in developing mathematical methods for studying the processes of heredity and evolution. He applied statistics to biological problems of heredity and evolution. From 1893-1912 he wrote 18 papers entitled Mathematical Contribution to the Theory of Evolution which contain his most valuable work. These papers contain contributions to regression analysis, the correlation coefficient and includes the chi-square test of statistical significance (1900). His chi-square test was produced in an attempt to remove the normal distribution from its central position. Pearson coined the term 'standard deviation' in 1893. His work was influenced by the work of Edgeworth and in turn influenced the work of Yule. Pearson had a long dispute with Fisher. Pearson used large sample which he measured and tried to deduce correlations. Fisher, on the other hand, followed Gosset in trying to use small samples and, rather than deduce correlations, to find causes. The dispute was bad enough to have Fisher turn down the post of Chief Statistician at the Galton Laboratory in 1919 since it would have meant working under Pearson....

Bsnl Training Essay Example

Bsnl Training Essay Example Bsnl Training Essay Bsnl Training Essay mzn, who permitted me for the practical training in their Department. I am also grateful to all Technical Staff of B. S. N. L. whose transcendent thoughts were the tremendous source of inspiration and encouragement, which will be definitely important for me as far my future is concerned. They explained primary techniques in a very easy manner. I also extend my gratitude to whole staff of B. S. N. L. , Muzaffarnagar, for their kind cooperation. CONTENTS Page No.  ¦ Company Profile 4-5  ¦ Vision, Mission and Objectives 6  ¦ Broadband Services 9 Technology Used 10  ¦ Wired Line 11-17  ¦ Wireless Line 18-26  ¦ Bibliography 12 COMPANY PROFILE On October 1, 2000 the Department of Telecom Operations, Government of India became a corporation and was christened Bharat Sanchar Nigam Limited (BSNL). Today, BSNL is the largest Public Sector Undertaking of India and its responsibilities include improvement of the already impeccable quality of telecom services, expansion of telecom network introduction of new telecom services in all villages and instilling confidence among its customers. Bharat Sanchar Nigam Ltd. formed in October, 2000, is Worlds 7th largest Telecommunications Company providing comprehensive range of telecom services in India: Wireline, CDMA mobile, GSM Mobile, Internet, Broadband, Carrier service, MPLS-VPN, VSAT, VoIP services, IN Services etc. Presently it is one of the largest leading public sector unit in India. BSNL has installed Quality Telecom Network in the country and now focusing on improving it, expanding the network, introducing new telecom services with ICT applications in villages and wining customers confidence. Today, it has about 47. 3 million line basic telephone capacity, 4 million WLL capacity, 48. 11 Million GSM Capacity, more than 37382 fixed exchanges, 44966 BTS, 3140 Node B ( 3G BTS), 287 Satellite Stations, 480196 Rkm of OFC Cable, 63730 Rkm of Microwave Network connecting 602 Districts, 7330 cities/towns and 5. Lakhs villages. BSNL is the only service provider, making focused efforts and planned initiatives to bridge the Rural-Urban Digital Divide ICT sector. In fact there is no telecom operator in the country to beat its reach with its wide network giving services in every nook corner of country and operates across India except Delhi Mumbai. Whether it is inaccessible areas of Siachen glacier an d North-eastern region of the country. BSNL serves its customers with its wide bouquet of telecom services. BSNL has set up a world class multi-gigabit, multi-protocol convergent IP infrastructure that provides convergent services like voice, data and video through the same Backbone and Broadband Access Network. At present there are 0. 6 million DataOne broadband customers. The company has vast experience in Planning, Installation, network integration and Maintenance of Switching Transmission Networks and also has a world class ISO 9000 certified Telecom Training Institute. BSNL cellular service, CellOne, has more than 49. 09 million cellular customers, garnering 16. 98 percent of all mobile users in its area of operation as its subscribers. In basic services, BSNL is miles ahead of its rivals, with 35. 1 million Basic Phone subscribers i. e. 85 per cent share of the subscriber base and 92 percent share in revenue terms. BSNL plans to expand its customer base from present 47 millions lines to 125 million lines by December 2007 and infrastructure investment plan to the tune of Rs. 733 crores (US$ 16. 67 million) in the next three years. The turnover, nationwide coverage, reach, comprehensive range of telecom services and the desire to excel has made BSNL the No. 1 Telecom Company of India. VISION, MISSION OBJECTIVES VISION: To become the largest telecom Service Provider in   Asia. MISSION: To provide world class State-of-art technology telecom services to its customers on demand at competitive prices. To Provide world class telecom infrastructure in its area of operation and to contribute to the growth of  the  countrys economy. OBJECTIVES: (1) To be the Lead Telecom Services Provider. (2) To provide mobile telephone service of high quality and become no. 1 GSM operator in its area of operation. (3) To provide point of interconnection to other service provider as per their requirement promptly. 4) Contribute towards: (i) National Plan Target of 500 million subscriber base for India by 2010. (ii) Providing telephone connection in villages as per government policy. (iii) Implementation of Triple play as a regular commercial proposition. (5) To facilitate R D activity in the country. Voice The majority of all telecommunication today uses Digital techniques, and the dominance of digital is so strong that in this text we will neglect Analog communication almost completely. When communicating voice digitally, the sound waves in the air must be digitalized. This is done by sampling the sound waves: measuring their shape, and converting this measurement into numbers. These numbers are a digital form of the voice signal. At the receiver, the measurement values (called samples) are used to reconstruct the original sound wave. To be able to reconstruct the voice with sufficient quality, the number of samples taken (called the Sampling-rate) and the accuracy of each sample (called the Resolution) must be sufficient. This is a trade-off, because the more samples, the more digital numbers needs to be transmitted, and this costs money. As a good compromise for understandable voice, the telecom community agreed to take 8000 samples per second, each 8 bits precise. This will not result into perfect audio-quality, but it is enough to understand the person on the other side of the line. As you are converting the sound waves to digital numbers, you create a continuous stream of information flow: every second you generate transport terminate 8000*8 = 64000 bits. This amount is called the Bit-rate. As a result a single digital voice connection is often referred to as a 64 kbps (kilo-bits-per-second). This continuous stream lasts as long as the phone conversation lasts, typically a few minutes. Note: As a comparison, an audio CD signal uses 44100 samples per second, each 16 bit precision, and two channels (left+right) to provide stereo. You will agree that CD sound quality is much better than a phone-line, but the price for this is that you need to transport 1. 411 Mbps for the CD (mega-bits-per-second), where only 64 kbps for a telephone line. Data When computers or machines communicate with each other, they usually dont send a continuous stream of information. Typically a computer needs some limited input data, then processes this, and responds with a limited amount of result data. Therefore data communication is using the concept of information packets a group of information bits. So one computer sends a packet of input to the other computer, which processes it, and then returns a packet with the results. BROADBAND SERVICES Broadband is often called high-speed Internet, because it usually has a high rate of data transmission. In general, any connection to the customer of 256 kbit/s (0. 256 Mbit/s) or more is considered broadband Internet. The Organization for Economic Co-operation and Development (OECD) has defined broadband as 256 kbit/s in at least one direction and this bit rate is the most common baseline that is marketed as broadband around the world. Telecommunication regulatory authority of India(TRAI) defines broadband as â€Å"an always on data connection that is able to support interactive services including internet access has the capability of the minimum download speed of 256Kbps to an individual subscriber from the point of presence of the service provider intending to provide broadband service where multiple uch individual broadband connections are aggregated the subscriber is able to access these interactive services including the internet through the POP. The interactive services will include any services for which a separate license is specifically required. For example- real time voice transmission, except to the extent that it is presently permitted under ISP license with internet Telephony†. TECHNOLOGY USED Broadband access technology is classified into two categories: Wired Line * DSL (Digital subscriber’s line) * Cable Modem * PLC (power line communication) * Optical fibre technologies Wireless Line * 3G Mobile Wi-Fi (Wireless fidelity) * Wi-Max * FSO (Free space optical) * LMDS MMDS * Satellite Wired Line: * DSL: Digital subscriber lines apply modern digital techniques on twisted pair medium to deliver new services over existing infrastructure. The bandwidth and quality of a typical analog telephone line is relatively low (300 3400 Hz). This is mainly because there is a wide variety of types, lengths, qualities, etc of twisted pairs used, and an analog line must assume the worst-case common denominator of all. However, todays more powerful signal processing and computing techniques allow building equipment hat adapts to each particular twisted pair, optimizing the use of it case by case, and resulting in much higher throughputs. For the Telecom operator, the advantages are: * No additional cable-cost: uses existing telephone line. * Telephone network is not used for data-services, like accessing the Internet. Telephone networks are dimensioned for phone calls, not for accessing the Internet. For example the average phone call duration is 100 seconds, when surfing the Internet this is much longer, resulting in congestion in the telephone network. Advantages for the end-user: High throughput up to Mbps. * Telephone is still available when surfing the Internet, telephone and data-services can be used at the same time. HDSL XDSL is a family name for a number of similar techniques. The x is a placeholder for several variants of Digital Subscriber Line (DSL). The first one, which was developed, was High Speed Digital Subscriber Line (HDSL) It is a symmetrical technique, the same bandwidth is available in both directions. HDSL is typically deployed in the network where 2. 048 Mbps are needed, but only twisted pair (no coax or fiber) is a vailable. ADSL Asymmetrical Digital Subscriber Line (ADSL) is the best-known variant of XDSL: The main principles are the same, but the bandwidths are divided Asymmetrical: more bandwidth is made available from network to user (Downstream) then from network to user (Upstream). This matches with typical residential applications, Such as: * Video-on-Demand (VOD): video, typically a few Mbps going downstream, with the user control (selecting the video, play, stop, rewind, etc) only a few kbps going upstream. * Internet: WEB-contents going downstream are megabytes; user requests are only a few hundred bytes. Figure: Internet Access Provider, ADSL VDSL Digital subscriber lines make a trade-off between bandwidth and distance: the shorter the line, the higher the throughput. As a result of this, a number of variants of DSL-techniques are being developed, from long distance – low bandwidth to short distance high bandwidth. Another parameter is the division of Upstream/Downstream bandwidth. This can be: * Symmetrical: the same in each direction, * Asymmetrical, fixed * Asymmetrical, dynamic: the total bandwidth, upstream+downstream is fixed, but at any time this total can be assigned in a certain ratio to either direction. New DSL variants using these new techniques are called Very High Speed Digital Subscriber Line (VDSL) Figure: Different DSL technique CABLE MODEM A cable modem with a splitter can provide Internet access to multiple PCs, if they are connected via a LAN. * Tuner converts TV channel to a fixed lower frequency (6 to 40 Mhz). * Demodulator performs A/D demodulation, error correction MPEG synchronization. * MAC extracts data from MPEG frames, filters data for other cable modem, runs the protocol. * Burst modulator performs RS encoding modulation frequency conversion/A conversion. Interface can be PCI bus, universal serial bus, Ethernet or others. Figure : -Cable Modem POWER-LINE COMMUNICATION(PLC) This is a new service still in its infancy that may eventually permit broadband Internet data to travel down standard high-voltage power lines. Broadband over power lines (BPL), also known as Power line communication, has developed faster in Europe than in the US due to a historical difference in power system design philosophies. Nearly all large power grids transmit power at high voltages in order to reduce transmission losses, then near the customer use step-down transformers to reduce the voltage. Since BPL signals cannot readily pass through transformers, repeaters must be attached to the transformers. In the US, it is common for a small transformer hung from a utility pole to service a single house. In Europe, it is more common for a somewhat larger transformer to service 10 or 100 houses. For delivering power to customers, this difference in design makes little difference, but it means delivering BPL over the power grid of a typical US city will require an order of magnitude more repeaters than would be required in a comparable European city. The second major issue is signal strength and operating frequency. The system is expected to use frequencies in the 10 to 30 MHz range, which has been used for decades by licensed amateur radio operators, as well as international shortwave broadcasters and a variety of communications systems (military, aeronautical, etc. ). However there are some disadvantages of using PLC communication: N/w characterstics devices can advesely affect signal strength quality. Electronic loads nearby high frequency radiation sources may cause high frequency noise that interferes BPL. Some PLC systems are not fully operable at very low or no load without battery backup. Physics limits frequency on power lines to ; 100 Mhz. BPL is not likely to be available soon for high voltage(;66Kv)power lines. Conventional electronic surge arrestors severely attenuate BPL signals. OPTIC-FIBRE TECHNOLOGY Currently fibre costs are high as compared to copper but there is a trend towards decreasing costs of optical fibre cables and photonics employed. To carry same information as one fibre cable we would need hundreds of reels of twisted wire copper cables. Fibre is 23 times lighter than copper cable 36 times less in cross section. Advantages Of Optic-Fibre Communication: Small Size and Weight: Optical fibers have very small diameters which are often no greater than the diameter of a human hair. Hence, even when such fibers are covered with protective coatings they are far smaller and much lighter than corresponding copper cables. This is a tremendous boon towards the alleviation of duct congestion in cities, as well as allowing for an expansion of signal transmiss ion within mobiles such as aircraft, satellites and even ships. Signal Security: The light from optical fibers does not radiate significantly and therefore they provide a high degree of signal security. Unlike the situation with copper cables, a transmitted optical signal cannot be obtained from a fiber in a noninvasive manner (i. e. without drawing optical power from the fiber). Therefore, in theory, any attempt to acquire a message signal transmitted optically may be detected. This feature is obviously attractive for military, banking and general data transmission (i. e. computer network) application. Ruggedness and Flexibility:- Although protective coatings are essential, optical fibers may be manufactured with very high tensile strengths. Perhaps surprisingly for a glassy substance, the fibers may also be bent to quite small radii or twisted without damage. Furthermore cable structures have been developed which have proved flexible, compact and extremely rugged. Taking the size and weight advantage into account, these optical fiber cables are generally superior in terms of storage, transportation, handling and installation to corresponding copper cables, whilst exhibiting at least comparable strength and durability. System Reliability And Ease Of Maintenance :- These features primarily stem from the low loss property of optical fiber cables which reduces the equirement for intermediate repeaters or line amplifiers to boost the transmitted signal strength. Hence with fewer repeaters, system furthermore, the reliability of the optical components is no longer a problem with predicted lifetimes of 20 to 30 years now quite common. Both these factors also tend to reduce maintenance time and costs. Enormous Potential Bandw idth: The optical carrier frequency in the range 1013 to 1016 Hz (generally in the near infrared around 1014 Hz or 105 GHz) yields a far greater potential transmission bandwidth than metallic cable systems. i. e. coaxial cable bandwidth up to around 500 MHz) or even millimetre wave radio systems (i. e. systems currently operating with modulation bandwidths of 700 MHz ). At present, the bandwidth available to fiber systems is not fully utilized but modulation at several gigahertz over a hundred kilometers and hundreds of megahertz over three hundred kilometers without intervening electronics (repeaters) is possible. Therefore, the information – carrying capacity of optical fiber systems has proved far superior to the best copper cable systems. Wireless Line: * Bluetooth: Bluetooth is a standard and communications protocol primarily designed for low power consumption, with a short range (power-class-dependent: 1 meter, 10 meters, 100 meters) based on low-cost transceiver microchips in each device. Bluetooth enables these devices to communicate with each other when they are in range. The devices use a radio communications system, so they do not have to be in line of sight of each other, and can even be in other rooms, as long as the received transmission is powerful enough. Bluetooth exists in many products, such as telephones, printers, modems and headsets. The technology is useful when transferring information between two or more devices that are near each other in low-bandwidth situations. Bluetooth is commonly used to transfer sound data with telephones (i. e. with a Bluetooth headset) or byte data with hand-held computers (transferring files). Bluetooth protocols simplify the discovery and setup of services between devices. Any Bluetooth device can, in theory, host any other Bluetooth device. This makes using services easier because there is no longer a need to set up network addresses or permissions as in many other network. More prevalent applications of Bluetooth include: Wireless control of and communication between a mobile phone and a hands-free headset. This was one of the earliest applications to become popular. Wireless networking between PCs in a confined space and where little bandwidth is required. Wireless communications with PC input and output devices, the most common being the mouse, keyboard and printer. Replacement of traditional wired serial communications in test equipment, GPS receivers, medical equipment, bar code scanners, and traffic control devices. For controls where infrared was traditionally used. Sending small advertisements from Bluetooth enabled advertising hoardings to other, discoverable, Bluetooth devices. Future of Bluetooth: * Broadcast Channel: enables Bluetooth information points. This will drive the adoption of Bluetooth into mobile phones, and enable advertising models based around users pulling information from the information points, and not based around the object push model that is used in a limited way today. Topology Management: enables the automatic configuration of the piconet topologies especially in scatternet situations that are becoming more common today. This should all be invisible to the users of the technology, while also making the technology just work. * Alternate MAC PHY: enables the use of alternative MAC and PHYs for transporting Bluetooth profile data. The Bluetooth Radio will still be used for device discovery, initial connection and profile configuration, however when lots of data needs to be sent, the high speed alternate MAC PHYs will be used to transport the data. This means that the proven low power connection models of Bluetooth are used when the system is idle, and the low power per bit radios are used when lots of data needs to be sent. * QoS improvements: enable audio and video data to be transmitted at a higher quality, especially when best effort traffic is being transmitted in the same piconet. Figure: -A typical Bluetooth USB dongle * 3-G Mobile: 2. 54 3 G falls into the category of broadband access. 2. 5G- GSM (EDGE/GPRS), CDMA 3G-VMTS/WCDMA, CDMA, speed achieved by 3G is 384K(M),2048K(S) Technology| 3G| Frequency Band| 1. 8-2. 5 GHz| Bandwidth| 5-20 MHz| Data Rate| Up-to 2 Mbps| Access| W-CDMA| FEC| Turbo-Codes| Switching| Cirsuit/Packet| Figure: -3G Services * Wi-Fi: A Wi-Fi enabled device such as a PC, game console, cell phone, MP3 player or PDA can connect to the Internet when within range of a wireless network connected to the Internet. The coverage of one or more interconnected access points - called a hotspot - can comprise an area as small as a single room with wireless-opaque walls or as large as many square miles covered by overlapping access points. Wi-Fi technology has served to set up mesh networks, for example, in London. Both architectures can operate in community networks. In addition to restricted use in homes and offices, Wi-Fi can make access publicly available at Wi-Fi hotspots provided either free of charge or to subscribers to various providers. Wi-Fi also allows connectivity in peer-to-peer (wireless ad-hoc network) mode, which enables devices to connect directly with each other. This connectivity mode can prove useful in consumer electronics and gaming applications. Figure : -A keychain size Wi-Fi detector. Operational advantages: Wi-Fi allows LANs (Local Area Networks) to be deployed without cabling for client devices, typically reducing the costs of network deployment and expansion. Spaces where cables cannot be run, such as outdoor areas and historical buildings, can host wireless LANs. * WiMAX WiMAX, an approximate acronym of Worldwide Interoperability for Microwave Access, is a telecommunications technology that provides for the wireless transmission of data using a variety of transmission modes, from point-to-point links to full mobile cellular-type access. The technology provides upto 70 Mb/sec symmetric broadband speed without the need for cables. The technology is based on the IEEE 802. 16 standard (also called WirelessMAN). The name WiMAX was created by the WiMAX Forum, which was formed in June 2001 to promote conformity and interoperability of the standard. Uses: The bandwidth and range of WiMAX make it suitable for the following potential applications: * Connecting Wi-Fi hotspots to the Internet. * Providing a wireless alternative to cable and DSL for last mile broadband access. * Providing data and telecommunications services. Providing a source of Internet connectivity as part of a business continuity plan. That is, if a business has a fixed and a wireless Internet connection, especially from unrelated providers, they are unlikely to be affected by the same service outage. * Providing portable connectivity. Comparison with Wi-Fi: Comparisons and confusion between WiMAX and Wi-Fi are frequent, possibly because both begin with the same two letters, are based upon IEEE standards beginning with 802. , and are related to wireless connectivity and Internet access. However, the two standards are aimed at different applications. WiMAX is a long-range system, covering many miles/kilometers that typically uses licensed spectrum (although it is possible to use unlicensed spectrum) to deliver a point-to-point connection to the Internet from an ISP to an end user. Different 802. 16 standards provide different types of access, from mobile (similar to a cellphone) to fixed (an alternative to wired access, where the end users wireless termination point is fixed in location. ) * Wi-Fi is generally a shorter range system, typically tens of yards/meters, though its range can be extended to over a kilometer using directional antennas. Wi-Fi uses unlicensed spectrum to provide access to a network. Typically Wi-Fi is used by an end user to access his/her own network, which may or may not be connected to the Internet. If WiMAX provides services analogous to a cellphone, Wi-Fi is similar to a cordless phone. * WiMAX and Wi-Fi have quite different Quality of Service (QoS) mechanisms. WiMAX uses a mechanism based on connections between the Base Station and the user device. Each connection is based on specific scheduling algorithms, which means that QoS parameters can be guaranteed for each flow. Wi-Fi has introduced a QoS mechanism similar to fixed Ethernet, where packets can receive different priorities based on their tags. This means that QoS is relative between packets/flows, as opposed to guaranteed. * WiMAX is highly scalable from what are called femto-scale remote stations to multi-sector maxi scale base that handle complex tasks of management and mobile handoff functions and include MIMO-AAS smart antenna subsystems. * LMDS: Local Multipoint Distribution Services (LMDS) is a radio-based access system. A fixed base-antenna (typically on a high building or tower) called Hub, services a number of users, which are also fixed. (Customer antenna on top of building). The access has a broadband capacity it can be used for all kinds of telecom services: * POTS or ISDN telephony. * Data services such as LAN interconnect, ATM, IP networks, etc. * Digital Video broadcasting. And potential customers are: * Businesses * Schools, Libraries, Health care providers * Residential consumers Each Hub is at the center of cell, a few kilometers in size, containing hundreds or thousands of users. Interconnections between hubs are typically done through fiber-optic core networks. The radio frequencies used are in the range 28 GHz to 42 GHz. This requires line-of-sight between hub and end-user. The word Local in LMDS refers to the relative short distance, or small cell-size. The words Multipoint Distribution refers to the point to multipoint nature. Figure 36: Local Multipoint Distribution Services * Free Space Optics (FSO): It is optical wireless, point-to-point line of sight broadband technology that is an alternative to fiber optic cable systems. It can transmit up to 1. 25 Gbps at a distance of 4 miles. * Satellite: It offers two-way Internet access via satellite orbiting the earth about 22000 miles above equator. PC through a special satellite modem broadcasts the requests to the satellite dish located on top of the roof / building which in turn transmits receives signal from the satellites. But it is slower in uplink as well as in downlink. BIBLIOGRAPHY (1) www. bsnl. co. in (2) www. wikipedia. org (3) www. howstuffworks. com (4) www. esnips. com